4 Measures of association

A measure of association compares the frequency of disease between exposed and unexposed people. This section defines the measures, derives their sampling distributions and confidence intervals, gives the tests of no association, and shows which measure each kind of case-control study estimates. Throughout, the \(2 \times 2\) table is laid out as in Section 1.2: \(a\) and \(b\) are the exposed and unexposed cases, \(c\) and \(d\) the exposed and unexposed non-cases, \(n_1 = a + c\), \(n_0 = b + d\), \(m_1 = a + b\), \(m_0 = c + d\).

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